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Trusted by 536 Independent Clinicians Who Recommend This product.
PureBioClinic Probiotic 40 Billion capsule bottle hero
Probiotic 40 Billion supplement formula and strains detail
Probiotic 40 Billion customer testimonial results
Probiotic 40 Billion daily gut health routine lifestyle
Probiotic 40 Billion capsule close-up and ingredients
PureBioClinic Probiotic 40 Billion vs competitors comparison
Probiotic 40 Billion supplement benefits infographic
Probiotic 40 Billion packaging and label detail
Probiotic 40 Billion gut health lifestyle image
PureBioClinic Probiotic 40 Billion product shot
Probiotic 40 Billion supplement full product view
PureBioClinic Probiotic 40 Billion capsule bottle hero
Probiotic 40 Billion supplement formula and strains detail
Probiotic 40 Billion customer testimonial results
Probiotic 40 Billion daily gut health routine lifestyle
Probiotic 40 Billion capsule close-up and ingredients
PureBioClinic Probiotic 40 Billion vs competitors comparison
Probiotic 40 Billion supplement benefits infographic
Probiotic 40 Billion packaging and label detail
Probiotic 40 Billion gut health lifestyle image
PureBioClinic Probiotic 40 Billion product shot
Probiotic 40 Billion supplement full product view

PureBioClinic® Probiotic 40 Billion

40 Billion Potent CFUs Daily
End Bloating & Gas Fast
Boost Immunity & Gut Balance
Feel Energised Light & Regular
Regular price £79.98 Sale price £39.99
SAVE 50%

Feel Ligther Everyday

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GMP Certified & UK Made

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FREE EXPRESS UK Delivery

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Free UK delivery On every order
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60-day guarantee Money back

30-day money-back guarantee. No questions asked. Delivered in 1-3 days.

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THE PROBLEM WITH MOST PROBIOTICS

Most Probiotics Are Dead Before You Swallow Them.

Standard probiotic capsules dissolve in stomach acid — pH as low as 1.5 — long before they reach your gut. Studies show up to 90% of live cultures in unprotected capsules don't survive the journey. If you've taken probiotics before and felt nothing, the bacteria never arrived. That's not a dosing problem. That's a delivery problem.
Up to 90%

of live cultures in standard capsules destroyed by stomach acid before reaching the gut.

pH 1.5

Stomach acid is aggressive enough to kill most unprotected probiotic strains within minutes.

No delivery system

Most probiotics use basic cellulose capsules with zero acid-resistance — your money, wasted.

THE PUREBIOCLINIC DIFFERENCE

The Capsule Engineered to Get There Alive.

MAKTREK® Bi-Pass Technology uses a complex marine polysaccharide matrix to shield live cultures through stomach acid — then dissolve precisely in the intestine where absorption happens. Four clinically researched strains. 40 billion CFU. Delivered where they need to be, not destroyed before they get there.
40 Billion
CFU per daily dose — delivered alive.
4 Strains
La-14 · Bl-04 · Lp-115 · Lpc-37
MAKTREK®
Acid-survival capsule technology.
Add to Cart — £39.99

How PureBioClinic® 40 Billion Compares

Probiotic 40 Billion
Typical High-Street Brand
Typical Budget Brand
CFU Count
✓ 40 Billion CFU
✗ 1–10 Billion CFU
✗ Under 1 Billion CFU
Acid-Survival Technology
✓ MAKTREK® Bi-Pass capsule
✗ Standard cellulose capsule
✗ No protection
Named Strains
✓ 4 researched strains (with codes)
✗ 1–2 generic strains
✗ Unnamed blend
Prebiotic (FOS)
✓ Included — feeds the cultures
✗ Rarely included
✗ Never included
Capsule Type
✓ Hypromellose — 100% vegan
✗ Often gelatin
✗ Often gelatin
Free From
✓ Gluten, lactose, corn, sugar
✗ Often contains fillers
✗ Often contains fillers
GMP Certified
✓ Yes
✗ Sometimes
✗ Rarely
Guarantee
✓ 30-Day Money-Back
✗ Rarely
✗ Rarely
Add to Cart — £39.99
🛡 30-Day Money-Back Guarantee — Zero Risk

What To Expect

DAYS 3–7

Cultures Colonising

The four strains begin establishing in your gut lining. You may notice subtle shifts — less bloating after meals, a little more regularity. This is the MAKTREK® capsule doing its job: cultures arriving alive, not destroyed in transit.

WEEKS 2–3

Gut Environment Shifting

Beneficial bacteria start to crowd out less helpful strains. Digestive comfort improves noticeably — less gas, less unpredictability. The FOS prebiotic is actively feeding the cultures, accelerating colonisation.

WEEKS 4–6

The Gut-Brain Connection

Your gut produces around 90% of your body's serotonin. As the microbiome rebalances, many people report steadier mood, clearer thinking, and better sleep quality. The kind of shift that's hard to explain until you feel it.

WEEKS 7–12

Full Microbiome Reset

This is where the compounding effect lands. Consistent digestion. Stronger immune response. More energy without the afternoon crash. A gut that works with you — not against you. Most customers reorder here.

Results vary by individual. For best results, take 2 capsules daily consistently for a minimum of 8 weeks.

What's Inside Every Capsule

Lactobacillus Acidophilus (La-14)

10 Billion CFU
+

Source: Clinically studied strain — part of 40B CFU proprietary blend

Supports gut barrier integrity and lactose digestion. One of the most researched Lactobacillus strains in peer-reviewed literature.

Bifidobacterium Lactis (Bl-04)

10 Billion CFU
+

Source: Clinically studied strain — part of 40B CFU proprietary blend

Associated with immune modulation and respiratory health in published research. Particularly studied for post-antibiotic microbiome recovery.

Lactobacillus Plantarum (Lp-115)

10 Billion CFU
+

Source: Clinically studied strain — part of 40B CFU proprietary blend

Studied for its role in reducing bloating, supporting gut motility, and maintaining intestinal barrier function.

Lactobacillus Paracasei (Lpc-37)

10 Billion CFU
+

Source: Clinically studied strain — part of 40B CFU proprietary blend

Research links this strain to reduced allergy symptoms, skin health via the gut-skin axis, and immune balance.

MAKTREK® Complex Marine Polysaccharide

60mg
+

Source: Marine-derived polysaccharide matrix (Bi-Pass Technology)

Acid-resistance delivery system. Shields live cultures through stomach acid (pH 1.5) and releases them in the intestine where absorption occurs. Not a probiotic strain — it's what gets them there alive.

Fructooligosaccharides (FOS)

24mg
+

Source: Plant-derived prebiotic fibre

Prebiotic — selectively feeds beneficial bacteria in the colon, accelerating colonisation and supporting microbiome diversity. Works synergistically with the four probiotic strains.

This product is a food supplement. Claims relating to specific probiotic strains are based on published research. No EU-authorised health claims are made for probiotic bacteria under Regulation (EC) No 1924/2006.

Strains Selected From Published Research

The four strains in Probiotic 40 Billion — Lactobacillus Acidophilus (La-14), Bifidobacterium Lactis (Bl-04), Lactobacillus Plantarum (Lp-115), and Lactobacillus Paracasei (Lpc-37) — are among the most studied probiotic strains in peer-reviewed literature. Research published in journals including Gut Microbes, Beneficial Microbes, and the British Journal of Nutrition has examined these strains for their role in gut barrier integrity, immune modulation, and microbiome diversity. We selected them because the evidence exists — not because they're cheap to source.

Gut Microbes

Beneficial Microbes

British Journal of Nutrition

HOW TO USE

Two Capsules. One Habit. Real Results.

1

Take

Swallow 2 capsules with a full glass of water. That's your full 40 billion CFU daily dose.

2

Time It Right

Take on an empty stomach — 30 minutes before your first meal — for optimal gut transit and colonisation.

3

Stay Consistent

Probiotic benefits compound over time. Clinical outcomes were observed after 4–12 weeks of daily use. Don't stop at week two.

💡

Pro tip: Store in a cool, dry place — no fridge needed. The MAKTREK® capsule keeps cultures stable at room temperature.

Dr. Hannah Weiss
Clinically Formulated

Dr. Hannah Weiss

MD, board-certified in Gastroenterology

With over 14 years of research in gut health and microbiome science, Dr. Weiss has dedicated her career to developing evidence-based wellness solutions.
Every formula we create is backed by rigorous clinical research and designed to deliver real, measurable results for your wellbeing.
Serena. G
Serena. G Verified

My bloating disappeared within 2 weeks and my digestion is finally normal. Clearer skin and more energy too! Best probiotics ever.

Caroline. L
Caroline. L Verified

After years of gut issues these 40 billion probiotics changed my life. Regularity is back, less discomfort, and I feel lighter.

Patricia. S
Patricia. S Verified

My skin cleared up dramatically, fewer breakouts and that healthy glow. Gut health really is everything.

Faith. N
Faith. N Verified

Bloating and bathroom issues gone after 3 weeks. I feel like a new woman. Highly recommend for women over 40.

Fabianna. L
Fabianna. L Verified

I sleep better, have steady energy, and no more afternoon crashes. These are the strongest probiotics I’ve tried.

Julieth. B
Julieth. B Verified

Improved mood, less anxiety, and perfect digestion. These probiotics deliver serious results.

Nathalie. P
Nathalie. P Verified

My IBS symptoms are almost nonexistent now. Flat stomach most days and better immunity.

Coralie. D
Coralie. D Verified

Clearer skin, less sugar cravings, and consistent energy. These 40 billion are powerful.

Stacy. D
Stacy. D Verified

Finally found probiotics that actually work. Gut feels balanced and my skin looks amazing.

Kimberley. O
Kimberley. O Verified

Reduced inflammation and bloating. I feel healthier overall after just one month.

Chloe. T
Chloe. T Verified

Bloating after every meal is finally gone. My stomach looks flatter and I have consistent energy all day. These are strong but gentle.

Ana. P
Ana. P Verified

My skin is clearer than it has been in years and digestion is smooth. I feel lighter and more comfortable in my clothes.

Dakota. D
Dakota. D Verified

After antibiotics these probiotics restored my gut fast. No more bathroom urgency and better mood overall.

Bernadette. H
Bernadette. H Verified

Less sugar cravings, steady energy, and perfect regularity. These 40 billion are the most effective I’ve tried.

Sarah. M
Sarah. M Verified

My IBS symptoms have calmed dramatically. I can eat without worry and my skin has a healthy glow again.

Brigitte. M
Brigitte. M Verified

This product has Improved my sleep and reduced my anxiety, the gut-brain connection is real! I feel balanced and healthy.

Tracy. C
Tracy. C Verified

No more afternoon fatigue. Digestion is excellent and bloating is rare. I recommend these to all my friends.

Celine. M
Celine. M Verified

Clearer skin, fewer breakouts, and a flatter tummy. These probiotics delivered visible results quickly.

Angela. K
Angela. K Verified

At 49 my hormones and gut were a mess. These helped restore balance and I feel so much better.

Karen. n
Karen. n Verified

Strong immunity this season, I haven’t been sick once. Plus amazing digestion and glowing skin. Love them!

FREQUENTLY ASKED QUESTIONS

Got Questions? We've Got Answers.

  • Most people's gut microbiomes are significantly depleted by diet, antibiotics, and stress. 40 billion CFU gives the beneficial strains a meaningful numerical advantage to establish and colonise. Studies on therapeutic probiotic use commonly use doses of 10–50 billion CFU daily.

  • Standard cellulose capsules dissolve in stomach acid (pH 1.5–3.5), killing most live cultures before they reach the intestine. MAKTREK® Bi-Pass Technology uses a complex marine polysaccharide matrix that resists stomach acid and dissolves in the intestine — where the bacteria actually need to be.

  • Most customers notice digestive changes within 3–7 days. Broader benefits — mood, energy, immune response — typically emerge at weeks 4–8. Gut microbiome rebalancing is a process, not an event. Consistency is everything.

  • Yes. The capsule is Hypromellose — 100% plant-derived. The formula contains no gelatin, no lactose, no animal-derived ingredients. Fully vegan-friendly.

  • Take probiotics at least 2 hours apart from antibiotics to avoid the antibiotic killing the live cultures. After a course of antibiotics, probiotics are especially beneficial for restoring microbiome diversity.

  • No. The MAKTREK® capsule technology keeps cultures stable at room temperature. Store in a cool, dry place away from direct sunlight — your kitchen cupboard is fine.

  • Yes — 30 days, no questions asked. If you're not satisfied for any reason, contact us and we'll refund you in full. We're confident enough in the product to back it completely.